We offer comprehensive genomic testing for healthcare, academia and pharmaceutical companies. Our ctDNA analysis pipeline is developed in an academic context and has been used to analyze over 2,000 blood samples. With Business Finland TUTLI funding, we are now translating our technology into a commercial offering to benefit cancer patients.
Two 10ml blood samples are collected into Streck cell-free DNA BCT tubes at regional laboratories and shipped to our facilities in Finland. Sample shipping is free of charge.
We extract cell-free DNA from the samples and sequence it using a panel capturing cancer associated genes. We computationally analyze millions of DNA fragments found in the patient's blood to construct a map of the genomic alterations driving the cancer.
We deliver a detailed report including information about genomic alterations, a list of identified biomarkers, available therapies, and relevant clinical trials. The report is delivered within 14 days of receiving the sample.
Our tailored panels encompass all genes of clinical interest in a specific cancer type. Cheaper and more informative than a pan-cancer panel, they are an optimal choice for patients with a known diagnosis. Starting price is 1200€ per sample, but discounts apply for larger orders. We currently offer tailored panels for six different cancer types:
ALK, ROS1, KRAS, TP53, KEAP1, EGFR, MET, ERBB2, SETD2, RB1, NF1, BRAF, MYC, MGA, CDKN2A
ESR1, ERBB2, EGFR, CYP19A1, NR3C3, PIK3CA, TP53, MYC, MDM4, AKT1, PTEN, BRCA1, BRCA2, ATM, PALB2, CCND1, KRAS
TP53, ARID1A, GATA3, KMT2C, KMT2D, PIK3CA, TSC1, PTEN, RB1, BRAF, CDKN1A, APC, ERBB2, STAG2, KDM6A, BRCA2, BRCA1, ATM, TXNIP
TP53, APC, KRAS, BRAF, MSH2, MSH6, MLH1, POLE, EGFR, ERBB2, ERBB3, ERBB4, FGFR3, MET, ALK, NTRK1, NTRK3
AR, TP53, BRCA2, BRCA1, ATM, PALB2, CDK12, PTEN, AKT1, PIK3CA, PIK3R1, SPOP, CHD1, FOXA1, HSD3B1, MSH2, MSH6, MLH1, MYC, CTNNB1, APC
TP53, NF1, BRCA1, BRCA2, ATM, PALB2, CDK12, KIT, MYC, MECOM, TERT, TERC, PIK3CA, CCNE1, KRAS, RB1
Our pan-cancer panel encompasses 105 genes that are frequently mutated across human cancers. We report somatic mutations and rearrangements in coding regions, a genome-wide copy number profile, and germline variants. Starting price is 2000€ per sample, but discounts apply for larger orders.
TP53, CDKN2A, CDKN1A, CDKN1B, CDK4, CDK6, CCND1, CCNE1, MDM2, MDM4, MYC, RB1, E2F3, MAP3K1, TP53BP1, STAG2
BRCA1, BRCA2, PALB2, MSH2, MSH6, MLH1, PMS2, ATM, ATR, CHEK2, CDK12, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, RAD51B, RAD51C
PTEN, PIK3R1, PIK3CA, PIK3CB, AKT1, AKT2, AKT3, TSC1
APC, CTNNB1, RNF43, RSPO1
NOTCH1, NOTCH2, NOTCH3
EGFR, ERBB2, ERBB3, ERBB4, FGFR3, MET
AR, ESR1, CYP19A1, FOXA1, NCOA2
KRAS, NRAS, HRAS, BRAF
ARID1A, ASXL1, CREBBP, DNMT3A, EP300, IDH1, KDM6A, KMT2C, KMT2D, SETD2, SMARCA1, TET2
BAP1, CHD1, ELF3, FBXW7, FOXP1, GATA3, GNAS, JAK1, KIT, MECOM, MED12, NKX3-1, PPARG, PTCH1, RUNX1, RYBP, SPOP, TBX3, TERT, TXNIP, UTY, XPO1, ZFHX3
For applications where longitudinal followup of patient tumor burden and clonal dynamics are needed, we offer assays tailored for an individual patient. These assays achieve the highest sensitivity at lowest cost, but are only applicable to patients whose cancer mutation profile is known. After establishing the mutation profile with a cancer specific panel or pan-cancer panel, the price for subsequent longitudinal analysis is 300€ per sample.
For samples where our standard panel identifies more than 5% tumor DNA, we provide extended analysis packages which can be purchased at extra cost.
We analyze the blood sample for all somatic mutations and germline variants in coding regions.
We analyze the entire cancer genome, providing a complete view of somatic mutations, copy number changes, and genomic rearrangements.
We wish to partner with healthcare providers, academic groups and pharmaceutical companies to provide best possible treatment for patients. Please contact us to discuss how your organization could benefit from partnership with Fluivia.
You can contact us by submitting a contact request below, or by emailing us at email@example.com.