Comprehensive skin cancer assay

The Fluivia comprehensive skin cancer assay detects somatic mutations, copy number changes, rearrangements and germline variants in 66 skin cancer genes. The test can be used with circulating tumor DNA, fresh frozen cancer tissue, or FFPE cancer tissue. The assay interrogates all genes that are recurrently altered at the DNA level in skin cancer, including genes related to RAS signaling, cell cycle regulation, PI3K signaling, chromatin remodeling, and telomerase activity. The assay also estimates a genome-wide copy number profile at 300 kb resolution, enabling absolute copy number quantification and detection of genome duplication events.

View example report


700 - 1500€ per sample, depending on order volume. Sample shipping and analysis of matched germline samples is free of charge.

Panel content

GeneAnalyzed regions
ALKCoding regions
APCCoding regions
ARID2Coding regions
ASPMCoding regions
BRAFCoding regions
CARD11Coding regions
CCND1Coding regions
CDK4Coding regions
CDKN2ACoding regions
CDKN2BCoding regions
COL1A1Coding regions
COL2A1Coding regions
EP400Coding regions
EPHA7Coding regions
ERBB4Coding regions
FAT1Coding regions
FAT4Coding regions
FGF3Coding regions
FGF4Coding regions
FGF19Coding regions
GRIN2ACoding regions
GRM3Coding regions
IL7RCoding regions
KDRCoding regions
KELCoding regions
KMT2ACoding regions
KMT2CCoding regions
KMT2DCoding regions
KSR2Coding regions
LIFRCoding regions
LRP1BCoding regions
MECOMCoding regions
MGACoding regions
MGAMCoding regions
MITFCoding regions
MYH11Coding regions
NF1Coding regions
NOTCH2Coding regions
NOTCH4Coding regions
NRASCoding regions
PAK5Coding regions
PCLOCoding regions
PDE4DIPCoding regions
PIK3C2GCoding regions
PPP6CCoding regions
PREX2Coding regions
PRKDCCoding regions
PTENCoding regions
PTPRBCoding regions
PTPRCCoding regions
PTPRDCoding regions
PTPRKCoding regions
PTPRTCoding regions
RAC1Coding regions
RELNCoding regions
RICTORCoding regions
ROS1Coding regions
SNCAIPCoding regions
SP140Coding regions
SPENCoding regions
TERTCoding regions + promoter
TP53Coding regions
TP63Coding regions
TRRAPCoding regions
USP6Coding regions
ZFHX3Coding regions
Whole genomeProbes tiled at 300 kb intervals for genome-wide copy number analysis


Our circulating tumor DNA analysis methodology has been validated in internationally leading studies comparing circulating tumor DNA profiles against time-matched metastatic tissue biopsies and diagnostic biopsies: