Comprehensive pancreatic cancer assay

The Fluivia comprehensive pancreatic cancer assay detects somatic mutations, copy number changes, rearrangements and germline variants in 44 pancreatic cancer genes. The test can be used with circulating tumor DNA, fresh frozen cancer tissue, or FFPE cancer tissue. The assay interrogates all genes that are recurrently altered at the DNA level in pancreatic cancer, including genes related to the RAS signaling pathway, cell cycle regulation, TGF-beta signaling, DNA repair, WNT signaling, PI3K signaling, and histone modification. The assay also estimates a genome-wide copy number profile at 300 kb resolution, enabling absolute copy number quantification and detection of genome duplication events.

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700 - 1500€ per sample, depending on order volume. Sample shipping and analysis of matched germline samples is free of charge.

Panel content

GeneAnalyzed regions
AKT2Coding regions
APCCoding regions
ARID1ACoding regions
ARID2Coding regions
ATMCoding regions
AVCR1BCoding regions
AVCR2ACoding regions
BRCA1Coding regions
BRCA2Coding regions
CCNE1Coding regions
CDKN2ACoding regions
CDKN2BCoding regions
CTNNB1Coding regions
GNASCoding regions
FAT1Coding regions
FAT4Coding regions
FBWX7Coding regions
GATA6Coding regions
KDM6ACoding regions
KMT2CCoding regions
KMT2DCoding regions
KRASCoding regions
LRP1BCoding regions
METCoding regions
MIB1Coding regions
MYCCoding regions
NOTCH1Coding regions
PBRM1Coding regions
PIK3CACoding regions
PTPRTCoding regions
PTPRSCoding regions
RBM10Coding regions
RELNCoding regions
RNF213Coding regions
RNF43Coding regions
SETD2Coding regions
SF3B1Coding regions
SMAD4Coding regions
SMARCA4Coding regions
TGFBR1Coding regions
TGFBR2Coding regions
TP53Coding regions
U2AF1Coding regions
ZFHX3Coding regions
Whole genomeProbes tiled at 300 kb intervals for genome-wide copy number analysis


Our circulating tumor DNA analysis methodology has been validated in internationally leading studies comparing circulating tumor DNA profiles against time-matched metastatic tissue biopsies and diagnostic biopsies: